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Oncogene AEG-1 strongly predicts response to erlotinib treatment in EGFR-mutant lung...

Spanish researchers have identified a gene whose expression level strongly predicts how well certain lung cancer patients will respond to treatment with the drug erlotinib. Dr Rafael Rosell and colleagues reported their findings at the European M...

Nanoparticles may enhance circulating tumor cell detection

Tiny gold particles can help doctors detect tumor cells circulating in the blood of patients with head and neck cancer, researchers at Emory and Georgia Tech have found. The detection of circulating tumor cells (CTCs) is an emerging technique tha...

Loss of gene promotes brain-tumor development, reduces survival, study finds

COLUMBUS, Ohio -- New research shows that loss of a gene called NFKBIA promotes the growth of glioblastoma multiforme, the most common and deadly form of brain cancer, and suggests that therapies that stabilize this gene may improve survival for c...

Penn researchers identify potential target for breast cancer therapy

PHILADELPHIA -- Overexpression or hyperactivation of ErbB cell-surface receptors drives the growth of many breast cancers. Drugs, like Herceptin, that block the receptors' signals halt tumor progression in some patients. However, not all pati...

Erlotinib improves progression-free survival as first-line therapy in advanced lung cancer

For patients with advanced lung cancer whose tumors carry EGFR activating mutations, first-line treatment with erlotinib nearly tripled progression-free survival compared to a standard chemotherapy combination, show results from the first prospect...

Vaccine extends glioblastoma patients’ survival in phase II trial

HOUSTON - A vaccine that turns the immune system against brain tumor cells bearing a genetic mutation that drives the most aggressive form of glioblastoma multiforme improved survival of patients in a phase II clinical trial, researchers at Duke...

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