Tag: journal of clinical investigation
Next-generation ALS drug silences inherited form of the disease in animal...
NIH-funded researchers delayed signs of amyotrophic lateral sclerosis (ALS)in rodents by injecting them with a second-generation drug designed to silence the gene, superoxide dismutase 1...
Potential new treatment for brittle bone disease
Patients with osteogenesis imperfecta (brittle bone disease) treated with teriparatide, a form of parathyroid hormone approved for treatment of women with osteoporosis, had stronger...
Broken cellular ‘clock’ linked to brain damage
A new discovery may help explain the surprisingly strong connections between sleep problems and neurodegenerative conditions such as Alzheimer’s disease. Sleep loss increases the...
Dilute bleach solution may fight skin damage, aging
Processes that age and damage skin are impeded by dilute bleach solution, according to a new study by researchers at the Stanford University School of...
Scientists Discover Important Wound-Healing Process
Scientists at The Scripps Research Institute (TSRI) have discovered an important process by which special immune cells in the skin help heal wounds. They found...
Stress-related protein speeds progression of Alzheimer’s
A stress-related protein genetically linked to depression, anxiety and other psychiatric disorders contributes to the acceleration of Alzheimer’s disease, a new study led by...
Silky brain implants may help stop spread of epilepsy
Silk has walked straight off the runway and into the lab. According to a new study published in the Journal of Clinical Investigation, silk...
Rapamycin: Limited anti-aging effects
The drug rapamycin is known to increase lifespan in mice. Whether rapamycin slows down aging, however, remains unclear. A team of researchers from the German...
Gene protects lung from damage due to pneumonia, sepsis, trauma, transplants
Lung injury is a common cause of death among patients with pneumonia, sepsis or trauma and in those who have had lung transplants. The damage often occurs suddenly and can cause life-threatening breathing problems and rapid lung failure.
The...
Unexpected new mechanism behind rheumatoid arthritis
A team of researchers at the University of Gothenburg, Sweden, has identified an enzyme that protects against inflammation and joint destruction. Made when the researchers blocked production of the enzyme GGTase-I in transgenic mice, this unexpected...
