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Targeted particle fools brain’s guardian to reach tumors

HOUSTON -- A targeted delivery combination selectively crosses the tight barrier that protects the brain from the bloodstream to home in on and bind to brain tumors, a research team led by scientists from The University of Texas MD Anderson Ca...

Study raises safety concerns about experimental cancer approach

A study by researchers at Washington University School of Medicine in St. Louis has raised safety concerns about an investigational approach to treating cancer. The strategy takes aim at a key signaling pathway, called Notch, involved in for...

Unfolding pathogenesis in Parkinson’s

The study, published in the Journal of Clinical Investigation, reveals that damaged alpha-synuclein proteins (which are implicated in Parkinson's disease) can spread in a 'prion-like' manner, an infection model previously described for diseases such...

Hepatitis C: In 2011, a predictive marker for response to therapy

Scientists at Inserm and Institut Pasteur have performed biomarker discovery on patients being treated for chronic hepatitis C infection. Their work, published in The Journal of Clinical Investigation, demonstrates that the plasma levels of the p...

Some cancer drugs may block cellular ‘cross talk’ but not kill...

AURORA, Colo. (Dec. 22, 2010) -- A class of drugs thought to kill cancer cells may in fact block "cross talk" between the cancer cell and normal immune cells, resulting in reduced cancer growth and spread -- a discovery that could significantly alte...

Vaccine boosts your immune system

YOUR BODY'S OWN VACCINE: Researchers at BRIC, the University of Copenhagen, have discovered for the first time a protein normally found in the body that can act to prevent chronic tissue inflammation. When administered in the form of a therapeut...

UT Southwestern researchers uncover culprits in life-threatening clotting disorder

DALLAS -- Dec. 3, 2010 -- Thanks to findings by UT Southwestern Medical Center researchers, individuals with a potentially life-threatening condition predisposing them to blood clots, or thrombosis, might someday receive therapy to prevent the...

Gene therapy for metastatic melanoma in mice produces complete remission

INDIANAPOLIS -- A potent anti-tumor gene introduced into mice with metastatic melanoma has resulted in permanent immune reconfiguration and produced a complete remission of their cancer, according to an article to be published in the December 2...

Study finds fat hormone’s long-sought link to heart protection

LA JOLLA, Calif., November 1, 2010 -- One of the many advantages of maintaining a normal body weight is having healthy fat, which in turn supports a healthy heart. Fat tissue is increasingly seen as more than just a storage depot -- it's als...

Scientists show Six3 gene essential for retinal development

New research led by St. Jude Children's Research Hospital investigators adds to evidence that the Six3 gene functions like a doorman in the developing brain and visual system, safeguarding the future retina by keeping the region where the eye is for...

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