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Inflammation inhibitor delivered directly to kidneys reverses course of destructive nephritis

Using a manmade version of a human antibody to directly deliver a drug that inhibits a powerful driver of inflammation, can reverse a disease...

Researcher lists more than 4,000 components of blood chemistry

After three years of exhaustive analysis led by a University of Alberta researcher, the list of known compounds in human blood has exploded from just a handful to more than 4,000. "Right now a medical doctor analyzing the blood of an ailing patie...

Experts call for greater awareness of the links between diabetes and...

The first time that many patients realise that diabetes can affect their kidneys is when they are referred to renal services, according to a multi-cultural study in the March issue of the Journal of Renal Care. UK researchers who spoke to 48 pati...

Why do some diabetics escape complications?

"The majority of diabetics will over time develop severe or fatal complications, but 10󈝻 per cent never do. They are the ones we are interested in in the PROLONG study", explains Valeriya Lyssenko, who along with Peter Nilsson, both from Lun...

‘Selective strategy’ recommended for CT scans in emergency departments

CINCINNATI--Emergency medicine researchers with the University of Cincinnati (UC) are advocating a new strategy for diagnosing a common but dangerous condition in the emergency room. Pulmonary embolism, or PE, is a potentially lethal disease in wh...

Mouse model offers new explanation for kidney disease and failure

Mice lacking only one copy of the gene for CD2-associated protein (CD2AP) appear to be significantly more susceptible to kidney disease and failure than normal mice. Moreover, the mutation appears to impair the elimination of proteins that accumulate in the kidney, a previously unidentified process.

Researchers Discover Possible New Mechanism for High Blood Pressure

Genetic differences that prevent tiny blood vessels from relaxing may be one reason why some people have high blood pressure, or hypertension, according to research led by scientists at Washington University School of Medicine in St. Louis. The findings are published in the February issue of the Journal of Clinical Investigation. "These findings provide new insights into the cause of hypertension and how normal blood pressure is regulated," says lead investigator Kendall J. Blumer, Ph.D., professor of cell biology and physiology. "This may lead to a way of determining the underlying cause of a person's hypertension and the most effective treatment for that individual."

19.2 Million U.S. Adults Have Chronic Kidney Disease

Eleven percent of the U.S. adult population has varying stages of chronic kidney disease, according to researchers from the Johns Hopkins Bloomberg School of Public Health. The researchers concluded that chronic kidney disease warrants improved detection and classification using standardized criteria to improve patient outcomes. Their research is published in the January 2003 issue of the American Journal of Kidney Diseases.

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