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Tighter ethics rules have reduced industrial relationship of NIH scientists

The 2005 ethics rules that govern relationships between researchers within the National Institutes of Health (NIH) and pharmaceutical, biotechnology and other industrial companies have significantly reduced the prevalence of such collaborations with...

Structural genomics accelerates protein structure determination

Proteins are molecular machines that transport substances, catalyze chemical reactions, pump ions, and identify signaling substances. They are chains of amino acids and the individual amino acid sequence is known for many of them. However, the funct...

Too much SP2 protein turns stem cells into ‘evil twin’ cancer...

Researchers at North Carolina State University have found that the overproduction of a key protein in stem cells causes those stem cells to form cancerous tumors. Their work may lead to new treatments for a variety of cancers. Dr. Jon Horowitz, as...

Entire issue of scientific journal devoted to center headed by Scripps...

LA JOLLA, CA, October 21, 2010 -- A multi-institutional consortium led by The Scripps Research Institute scientists, the Joint Center for Structural Genomics (JCSG), is the sole focus of a special issue of the journal Acta Crystallographica Sectio...

NIH-funded scientists sequence genomes of lyme disease bacteria

WHAT: Scientists supported by the National Institutes of Health (NIH) have determined the complete genetic blueprints for 13 different strains of Borrelia burgdorferi, the bacteria that cause Lyme disease. The achievement should lead to a better un...

Vitamin D-ficiency common among orthopaedic surgery

Forty-three percent of patients scheduled to undergo orthopaedic surgery have insufficient levels of vitamin D and two out of five of those patients had levels low enough to place them at risk for metabolic bone disease, according to a study publish...

Developments in nanobiotechnology at UCSB point to medical applications

(Santa Barbara, Calif.) -- -- Two new groundbreaking scientific papers by researchers at UC Santa Barbara demonstrate the synthesis of nanosize biological particles with the potential to fight cancer and other illnesses. The studies introduce new...

AACR supports NIH stem cell research

PHILADELPHIA -- The American Association for Cancer Research (AACR), the world's oldest and largest cancer research organization, reiterates its support for the responsible conduct of human embryonic stem cell research that, up until this week, wa...

Gene Enhances Prefrontal Function at a Price

Studies of a gene that affects how efficiently the brain's frontal lobes process information are revealing some untidy consequences of a tiny variation in its molecular structure and how it may increase susceptibility to schizophrenia. People with a common version of the gene associated with more efficient working memory and frontal lobe information processing may pay a penalty in adverse responses to amphetamine, in heightened anxiety and sensitivity to pain. Yet, another common version may slightly bias the brain toward a pattern of neurochemical activity associated with psychosis, report researchers at the National Institutes of Health (NIH).

Gene discovery may shed light on carpel tunnel syndrome and Lou...

Scientists at the National Human Genome Research Institute (NHGRI) and at the National Institute of Neurological Disorders and Stroke (NINDS) have identified the gene responsible for two related, inherited neurological disorders, and have, for the first time, directly implicated this gene and its enzyme product in a human genetic disease.

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