Genetic differences that prevent tiny blood vessels from relaxing may be one reason why some people have high blood pressure, or hypertension, according to research led by scientists at Washington University School of Medicine in St. Louis. The findings are published in the February issue of the Journal of Clinical Investigation. “These findings provide new insights into the cause of hypertension and how normal blood pressure is regulated,” says lead investigator Kendall J. Blumer, Ph.D., professor of cell biology and physiology. “This may lead to a way of determining the underlying cause of a person’s hypertension and the most effective treatment for that individual.”