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Think small when powering today's electronic soldier

On the battlefield, having a reliable source of power to operate the many advanced electronic devices a soldier carries is essential. But today’s heavy and cumbersome batteries fall short in satisfying the military’s needs. In search of both a lightweight and reliable alternative, the Department of Energy’s Pacific Northwest National Laboratory has developed the smallest power system yet, all wrapped up in a micro-sized package.

New antibody library speeds search for new detection tools

Scientists at the Department of Energy’s Pacific Northwest National Laboratory have extracted part of the human immune system and reconstituted it in brewer’s yeast in a fashion that enables powerful machines to quickly identify new antibodies. The advance could have major repercussions for fundamental biological science as well as industries that use antibodies for sensors, biodetectors, diagnostic tools and therapeutic agents.

Scientists identify 490 proteins in human blood serum

Researchers have identified or confirmed 490 proteins in human blood serum — nearly doubling the number of known serum proteins, according to a paper accepted for publication in the December issue of Molecular and Cellular Proteomics. “We have performed the most extensive identification of proteins in serum to date,” said Joel Pounds, corresponding author and a PNNL staff scientist. “We studied blood serum because it holds clues to all the major processes in our bodies. We need to know what proteins exist in that serum to know how they might be used to predict disease susceptibility, monitor disease progression or diagnose disease.” These clues include proteins that “leak” from dead and dying cells, and proteins secreted into blood or released from tumors. Identifying these proteins allows scientists to conduct additional studies to define each protein’s functional role in cells and the body.