Penn researchers find new role for cancer protein p53

PHILADELPHIA – The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins. No…

Research shows how bacteria communicate with each other

Jerusalem, March 1, 2011 — A pathway whereby bacteria communicate with each other has been discovered by researchers at the Hebrew University of Jerusalem. The discovery has important implications for efforts to cope with the spread of harmf…

Common congenital defect a prickly problem for the kidney

One of the most common congenital defects in humans — it is detected in approximately 0.5% of fetuses analyzed by routine antenatal sonography — is a kidney abnormality known as hydronephrosis. Hydronephrosis arises because the flow of urine f…

Nailing down a crucial plant signaling system

Stanford, CA — Plant biologists have discovered the last major element of the series of chemical signals that one class of plant hormones, called brassinosteroids, send from a protein on the surface of a plant cell to the cell’s nucleus. Although …

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