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Penn researchers find new role for cancer protein p53

PHILADELPHIA - The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins. No...

Research shows how bacteria communicate with each other

Jerusalem, March 1, 2011 -- A pathway whereby bacteria communicate with each other has been discovered by researchers at the Hebrew University of Jerusalem. The discovery has important implications for efforts to cope with the spread of harmf...

Signaling path in brain may prevent that ‘I’m full’ message, UT...

DALLAS -- March 1, 2011 -- Researchers at UT Southwestern Medical Center have identified a signaling pathway in the brain that's sufficient to induce cellular leptin resistance, a problem that decreases the body's ability to "hear" that it is full...

ISU research raises hope for solving Parkinson’s disease puzzle

AMES, Iowa - A protein pathway that may hold the secret to understanding Parkinson's disease has been discovered and explained by Iowa State University researchers. Anumantha Kanthasamy, a distinguished professor of biomedical sciences and t...

Common congenital defect a prickly problem for the kidney

One of the most common congenital defects in humans -- it is detected in approximately 0.5% of fetuses analyzed by routine antenatal sonography -- is a kidney abnormality known as hydronephrosis. Hydronephrosis arises because the flow of urine f...

Communication pathways within proteins may yield new drug targets to stop...

INDIANAPOLIS -- A School of Science at Indiana University-Purdue University Indianapolis biophysicist has developed a new method to identify communication pathways connecting distant regions within proteins. With this tool, Andrew J. Rader...

Scripps Research scientists reveal key mechanism governing nicotine addiction

JUPITER, FL -- January 25, 2011 -- Embargoed by the journal Nature until January 30, 1 PM Eastern time -- Scientists from the Florida campus of The Scripps Research Institute have identified a pathway in the brain that regulates an individual's v...

Scientists link protein to the insulation of the nervous system’s wiring

CHAPEL HILL, N.C. -- Researchers at the University of North Carolina at Chapel Hill have pinpointed a crucial function for a key player in the development of the nervous system. They found that this player -- a protein called Erk -- is necessary ...

Nailing down a crucial plant signaling system

Stanford, CA -- Plant biologists have discovered the last major element of the series of chemical signals that one class of plant hormones, called brassinosteroids, send from a protein on the surface of a plant cell to the cell's nucleus. Although ...

Neural stem cells maintain high levels of reactive oxygen species

For years, the majority of research on reactive oxygen species (ROS) — ions or very small molecules that include free radicals — has focused...

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