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Estrogen plus progestin not helpful to quality of life in postmenopausal women

Taking a combination of the hormones estrogen and progestin does not improve the quality of life for women who are free of menopause-related symptoms, but does expose them to a slightly higher risk of heart attacks, strokes and breast cancer, a new multi-center national study concludes. For that reason, medical scientists now recommend against the combined therapy in the absence of such symptoms.

Animal studies confirm hormone replacement can improve learning

For estrogen to enhance learning and memory, nerve cells in the brain called cholinergic neurons are essential to the process, suggest animal studies performed by researchers from the University of Pittsburgh School of Pharmacy. “Estrogen replacement in postmenopausal women has important effects on mood and cognition. This research was focused on trying to understand what estrogen does in the brain to reduce the effects on brain aging and cognitive decline,” said Robert Gibbs, associate professor of pharmaceutical sciences at the University of Pittsburgh School of Pharmacy.