A group of Canadian researchers has found the most direct evidence to date that people with early-stage Alzheimer Disease can engage additional areas in the brain to perform successfully on memory tests. Alzheimer’s is a progressive, degenerative disease that affects an individual’s ability to think, remember, understand and make decisions. People with early-stage Alzheimer’s begin to experience problems with their episodic and semantic memory. Semantic refers to the accumulation of general world knowledge gained over a lifetime (for example, names of countries, famous people, major historical events). Episodic refers to events that one experiences throughout his/her life (for example, having visited the dentist yesterday, or graduating from college back in 1950).