Finding could lead to new tumor immunotherapy targeting pivotal CTLA-4 protein A major discovery that brings a new drug target to the increasingly exciting landscape of cancer immunotherapy was published yesterday by researchers from La … Read more
Scientists at The Scripps Research Institute (TSRI) have developed a method for modifying organic molecules that significantly expands the possibilities for developing new pharmaceuticals and improving old ones. “This is a technology that can be … Read more
A new “fluid biopsy” technique that could identify patients at high risk of a heart attack by identifying specific cells as markers in the bloodstream has been developed by a group of researchers at The … Read more
A team of researchers has published new findings on a system in the brain that naturally moderates the effects of stress. The findings confirm the important role of the stress-damping system called the nociceptin system, … Read more
Scientists at The Scripps Research Institute (TSRI) have demonstrated a drug-discovery strategy with a double payoff—it enables the rapid selection of chemical compounds that have a desired effect on cells and also highlights how the … Read more
The generic anticonvulsant medication gabapentin shows promise as an effective treatment for alcohol dependence, based on the results of a 150-patient clinical trial of the medication. Conducted by scientists supported by the National Institute on … Read more
Scientists at The Scripps Research Institute (TSRI) have identified a set of compounds that may be used to treat multiple sclerosis (MS) in a new way. Unlike existing MS therapies that suppress the immune system, … Read more
Scientists at The Scripps Research Institute (TSRI) have discovered key details of a brain-to-body signaling circuit that enables roundworms to lose weight independently of food intake. The weight-loss circuit is activated by combined signals from … Read more
Nocturnal animals need their noses to stay alive. Mice, among others, depend on their impressive olfactory powers to sniff out food or avoid danger in the dark. Hard-wired to flee a predator or fight a … Read more
Scientists at The Scripps Research Institute (TSRI) have discovered an important process by which special immune cells in the skin help heal wounds. They found that these skin-resident immune cells function as “first responders” to … Read more
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