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Cerebral palsy symptoms improve with botulinum toxin

Children with cerebral palsy show long-term improvement through treatment with botulinum toxin, according to new research. Children treated with the drug had improvements ranging from making voluntary movements for the first time to improved stance and walking, according to the study’s lead author, neurologist Marc P. DiFazio, MD, of Walter Reed Army Medical Center in Washington, DC.

First step towards detecting exposure to biowarfare agents

Army researchers are laying the groundwork for what one day could be a test to identify individuals who have been exposed to biological agents. They present their findings today at the American Society for Microbiology’s Biodefense Research Meeting. “Recent events have demonstrated that assessing exposure to a biological threat agent well in advance of onset of illness or at various stages post-exposure would be an important capability to have among the diagnostic options,” says Marti Jett of the Walter Reed Army Institute of Research, the scientist directing the study.

Brain injury test may be health care boon

U.S. soldiers fighting in today’s high-tech military force will be much more likely to survive traumatic brain injuries if University of Florida researchers succeed in developing a blood test to assess the severity of head wounds on the battlefield, U.S. Department of Defense officials say. Such a test can’t come soon enough for the department, which has allocated $2.2 million to help scientists at UF’s McKnight Brain Institute and the Walter Reed Army Institute of Research develop the first routine diagnostic tool to define the scope of such injuries. Penetrating brain injuries claim 25 percent of soldiers killed in battle, according to department officials, yet there is no effective way to diagnose traumatic brain injury short of a brain scan, which is not practical in combat settings.

When rashes kill

A new reports says that up to half of all U.S. residents may be ineligible for smallpox vaccination because of the growing incidence of eczema. In a report appearing in the September issue of the Journal of Allergy and Clinical Immunology, Dr. Renata J.M. Engler from the Walter Reed Army Medical Center in Washington, DC, and colleagues note that in people with eczema, exposure to vaccinia — a relative of smallpox used to inoculate people — or even contact with someone who was recently vaccinated can cause a condition that can lead to scarring, blindness and even death. “A major challenge lies in the ability to protect the population from the disease while minimizing the considerable side effects from the vaccine,” Reuters quotes from their report. The researchers say more studies should be conducted to help identify people who are prone to side vaccinia effects. Others who should avoid smallpox vaccination include people with immune deficiency diseases such as AIDS, and those on immune system-suppressing drugs, such as transplant patients.