One Week, Two Innovations in Aging and Health

Incremental advances in understanding the genetics, epigenetics, and biochemistry of aging are gradually pushing the field forward.  In addition, there are occasional new ideas that have the potential for quantum advances that change the nature of the game.  Last week, there were two game-changers, originating from the US East and West coasts. Caloric Restriction has … Read more

Dreams of a Pill to Enable Regeneration

Eight years ago, I assumed erroneously that the chute of my food processor was longer than my fingers.  I lost a quarter inch from the tip of my right middle finger.  Today, my finger has grown back, right down to the pattern of the fingerprint.  I am fortunate to be a good healer.  This is … Read more

Is there an Aging Clock in the Hypothalamus?

The brain does its work with electrical signals through a network of neurons.  The information is passed to every cell in the body with chemical signals, hormones, RNAs and proteins that are dissolved in the blood.  The interface between the electrical and the chemical networks is a tiny region in the middle of the brain, … Read more

Preserving Insulin Sensitivity

The body adjusts its rate of aging in response to environmental cues.  Most influential is diet.  The story I have told is that The body decies whether food is plentiful (for pregnancy and childrearing) by sensing nutrition and body fat. The body decides either “reproduce and die” or “hang in there and live longer”. The … Read more