ATLANTA — The American College of Rheumatology today announced the release of two new provisional definitions of rheumatoid arthritis remission, which are to be applied to future RA clinical trials.
According to research presented in the March …
Tag Archives | arthritis rheumatism
Rheumatoid arthritis researchers redefine remission
Researchers uncover link to increased atherosclerosis risk in lupus patients
Researchers in China have demonstrated interferon-alpha (IFN-a) is associated with increased risk of atherosclerosis in patients with systemic lupus erythematosus (SLE). For the first time, IFN-a priming was shown to promote lipid uptake and foam ce…
Fostamatinib proven to be safe but not effective
In a previous study, rheumatoid arthritis (RA) patients who failed to respond to methotrexate were shown to experience positive results with fostamatinib disodium (R788), an oral spleen tyrosine kinase (Syk) inhibitor that is thought to block immune…
When you can’t walk fast enough to cross busy streets
CHICAGO — When a traffic light at a busy intersection flashes the WALK sign, people with knee osteoarthritis worry they can’t walk fast enough to make it across the street in time. New Northwestern Medicine research shows people with this common a…
Current smokers with early rheumatoid arthritis less responsive to TNF inhibitors, methotrexate
Patients with early rheumatoid arthritis (RA) who are current smokers were less likely to achieve good response to methotrexate (MTX) and tumor necrosis factor (TNF) inhibitors than those who never smoked. The study by researchers from Sweden also f…
Accurate interpretation of antinuclear antibodies test key to confirming autoimmune disease
The presence of antinuclear antibodies (ANA) indicates the possibility of autoimmunity and the indirect immunofluorescence (IIF) assay on HEp-2 cells is the standard blood test (ANA-HEp-2) used to detect ANA. However, studies have shown that a “fals…
Lower back and foot pain associated with more severe knee osteoarthritis symptoms
A new study found that patients with osteoarthritis (OA) of the knee who also have pain in other joints were more likely to experience greater knee pain. Specifically, pain in the lower back as well as foot pain and elbow pain on the same side as th…
Etanercept helps restore normal growth in children with juvenile arthritis
Researchers from the Cincinnati Children’s Hospital Medical Center observed a statistically significant increase in mean height, weight, and body mass index (BMI) percentiles in patients with juvenile idiopathic arthritis (JIA) who were treated with…
Study finds bortezomib to be promising treatment for rheumatoid arthritis
A new study by Greek researchers suggests that the biologic drug bortezomib (Velcade), a proteasome inhibitor used to treat multiple myeloma (bone marrow cancer), may represent a promising treatment for rheumatoid arthritis (RA). In this study, bort…
Black women with SLE develop cardiovascular disease at early age
A recent study by researchers at Penn State College of Medicine found significant racial disparities in the age of systemic lupus erythematosus (SLE) patients at the time of hospital admission for cardiovascular disease (CVD) events and CVD-related …
Novel autoantibodies identified in patients with necrotizing myopathy
Researchers at Johns Hopkins University School of Medicine have identified a subgroup of patients with necrotizing myopathy who have a novel autoantibody specificity that makes them potential candidates for immunosuppressive therapy. The complete st…