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This image is an artistic representation of how APOE2 promotes resilience to cellular senescence maintaining the integrity of DNA and the nuclear envelope. We show a neuron protected by APOE2 represented as orange dots across the cell, with a blue mesh representing the resistance to senescence. We highlight in golden the integrity of the nucleus and the protected genome.

APOE2 Keeps Neurons Young by Fixing Their DNA Before It Falls Apart

The new drug carrier (shown as blue-red strands) is split by an enzyme (purple structure), delivering the therapeutic (blue spheres) to a cancerous cell.

A Molecular Grappling Hook Could Keep Cancer Drugs Trapped Inside Tumors

A hearing system monitoring this man’s brain activity amplifies a conversation played on his left while quieting one on his right, based on which conversation his brainwaves suggest he is paying attention to.

Scientists Have Built a Hearing System That Tunes In to Whatever Your Brain Is Focusing On

spicolli fast times at ridgemont high

Why Regular Cannabis Users Have Lower Rates of Type 2 Diabetes

a museum scene

Visiting a Museum Once a Week Slows Biological Aging as Much as Regular Exercise

vegan food

Four Weeks of Eating Differently Can Make Your Body Biologically Younger, New Study Finds

The Hidden Wiring Inside Brown Fat That Controls How Well It Burns Energy

Molecule in Brown Fat Could Transform Bone Disease Treatment

Trial participant Kim Garland (left) reviews a scan with the study’s primary investigator, Tanner Johanns, MD, PhD, a WashU Medicine oncologist

A Custom-Built Vaccine Is Helping the Immune System Fight the Deadliest Brain Cancer

A patient treated with the NG101 antibody during occupational therapy. (Image: University Hospital Balgrist)

The Protein That Blocks Nerve Repair After Spinal Cord Injury Has Been Stopped

Qiaofeng Ye, left, and Idan Shalev, the lead and senior authors of this research, in their laboratory at Penn State University Park. Credit: Dennis Maney / Penn State. Creative Commons

Abuse Leaves Measurable Biological Marks in Children’s Bodies Within a Year

metformin bottle and pills

The World’s Most Prescribed Diabetes Drug Has Been Working in the Wrong Organ

jellyfish

The Jellyfish Clogging Fishing Nets Could Be Funding the Future of Medicine

An electronic 96-channel pipette was one of the tools used to scale up and allow the team to perform over 7,000 parallel experiments that uncovered more than 100 bNAb escape mutations across 15 viral strains.

Most HIV Strains Can Escape the Immune System’s Best Antibodies With a Single Mutation

Prostate cancer grading uses the Gleason score (6-10) and Grade Group (1-5) systems to estimate cancer aggressiveness based on how the cells look under a microscope. Higher numbers indicate faster-growing, more aggressive cancer.

Urine Test Cuts Unnecessary Prostate Biopsies by Nearly Two-Thirds in Head-to-Head Trial Against MRI

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