The Melanoma Molecular Map Project (http://www.mmmp.org) collects in a systematic way news regarding melanoma research advances. Moreover, it provides users with six interconnected databases gathering scientific information on molecules and drugs necessary to develop targeted therapy against the deadliest type of skin cancer. Is the time mature to exploit the huge amount of literature on cancer biology to develop targeted therapy ? Everybody seems to talk about it, but nobody actually seems to do much about it.