Genetic profiling could improve IVF success

There are three sources of variability in fertility - genetics, the family environment and the individual environment.

by Frieda Klotz Genetic profiling could help determine whether an embryo created through in-vitro fertilisation (IVF) is likely to successfully transfer to the womb, increasing the success rate of the procedure. It’s part of a field of work looking at the role of genetics in fertility. ‘Understanding why some people do not have children, and … Read more

Ultrafine pollution particles create air of menace

As many as 6.5 million premature deaths every year are attributed to air pollution, according to the World Health Organization.

An air quality study has for the first time detected nano-sized particles of air pollution in children’s urine. With a diameter of just 100 nanometers – a thousandth of the width of a human hair – these ultrafine particles are the smallest particles found in air pollution and have been linked to heart disease and respiratory conditions … Read more

Omics, sweet omics – curing the incurable, one disease at a time

In recent years, the genetic defects behind about 5,000 of the estimated 7,000-8,000 rare diseases have been discovered, largely thanks to omics.

There are many rare genetic diseases that strike perhaps only one in a million people. Often incurable, they can be profoundly debilitating and frequently life-threatening. Though each particular disease is rare, they number in the thousands – which means that together they affect about 30 million Europeans or around 7% of us. Treating these diseases is challenging … Read more

Why get a filling when you could print a new smile?

A new material printed onto teeth could help the approximately one in 10 people who suffer from dental sensitivity caused by worn enamel.

by Ethan Bilby Twinges. Painful teeth. About one in 10 people suffer from dental sensitivity caused by worn enamel. But rather than providing short-term solutions like special toothpastes or fillings, new techniques could print whole new layers of enamel onto teeth – or even stimulate the body to grow new ones. Dr Antonios Anastasiou wants to … Read more

Maternal death audits in Africa win €1 mn innovation prize

A successful project to improve childbirth safety in Mali and Senegal will now be rolled out to Chad, Niger and Burkina Faso.

An audit committee that reviews deaths during childbirth has reduced the maternal mortality rate in hospitals in Mali and Senegal by 15%, and its founders have been awarded the €1 million EU Horizon Birth Day prize for a solution that saves the lives of mothers and their babies. More than 800 women die every day from preventable … Read more

Simple blood test could reveal epilepsy risk

It is difficult for doctors to diagnose epilepsy as they usually do not observe the symptoms in a patient, but a blood test could overcome this challenge.

A finger-prick blood test to diagnose epilepsy could be available within five years, according to scientists who are using tell-tale molecules called biomarkers to overcome current diagnostic problems and guide treatment. More than 50 million people are affected by epilepsy worldwide. However, diagnosing the disease remains challenging and treatments are often unsuccessful: only 70% of patients taking … Read more