An experimental drug delivering the potency of two cups of strong coffee and a mixed drink has been shown to limit stroke-induced brain damage in animals. Now, this agent has been demonstrated to be safe in a small pilot study of ischemic stroke patients reported in today’s rapid access issue of Stroke: Journal of the American Heart Association.
High levels of the inflammation marker C-reactive protein (CRP) in healthy, middle-aged men signals an increased risk of ischemic stroke in later life, according to a 20-year follow-up study reported in today’s rapid access issue of Circulation: Journal of the American Heart Association. In this study, men with few cardiovascular risk factors but with the highest CRP levels studied had a 3.8-fold increased incidence of stroke in 10 to 15 years compared to men with the lowest levels, says lead author J. David Curb, M.D., of the Pacific Health Research Institute and the Department of Geriatric Medicine and Medicine at the University of Hawaii in Honolulu.
An analysis of hundreds of published studies on the safety and effectiveness of low-carbohydrate diets found that there is not enough scientific evidence for or against the use of these diets. “This analysis is important because it clearly documents the lack of hard scientific data to support the use of low-carbohydrate diets, and identifies areas that need further research. Both the public and health-care professionals should pay close attention to this wealth of data, collected from many different research groups, because it is the most comprehensive review of published science on the subject to date,” says Robert H. Eckel, M.D., the chair of the American Heart Association’s Nutrition, Physical Activity and Metabolism Council.
People with a certain form of a gene that influences blood flow may have a lower risk of having a heart attack and dying from heart disease, according to a new study in today’s rapid access issue of Circulation: Journal of the American Heart Association. The gene controls variations in beta-2 adrenergic receptors, which are on the surface of heart muscle cells and blood vessel cell walls. When activated by adrenaline and noradrenaline, these receptors set in motion a series of events that dilate the blood vessels and increase heart rate.
Eating fish regularly reduced the risk of heart disease in diabetic women by as much as 64 percent, according to a new study. “We found that women with type 2 diabetes who ate more fish had significantly lower risk of coronary heart disease and total death than those who rarely ate fish,” says Frank B. Hu, M.D., lead author and associate professor of nutrition and epidemiology at the Harvard School of Public Health in Boston. “Previous studies have found that fish consumption reduces risk of heart disease in a largely healthy population. This is the first study to look at the relationship among diabetic patients, who have very high risk of heart disease.”
Vitamin C helped convert mouse embryonic stem cells growing in the laboratory to heart muscle cells, researchers report. This basic-research discovery could lead to future research on ways to treat people suffering from damaged heart muscle. “Although the findings of this study are very preliminary with respect to their impact on human lives, this line of research has enormous implications for the future care of thousands of patients who develop heart failure each year,” says Robert O. Bonow, M.D., president of the American Heart Association.
Men who smoke increase their risk for hemorrhagic stroke every time they light up, and smoking more than a pack of cigarettes a day doubles their risk compared to nonsmokers or men who’ve kicked the habit, according to a long-term prospective study reported in today’s rapid access issue of Stroke: Journal of the American Heart Association.
Taking cholesterol-lowering drugs before undergoing artery-clearing procedures appears to reduce deaths, heart attacks, and recurrent blockages among patients with elevated levels of an inflammation marker, according to research reported in today’s rapid access issue of Circulation: Journal of the American Heart Association. Previous studies have suggested that taking a class of cholesterol-lowering drugs called statins after percutaneous coronary interventions (PCI) such as balloon angioplasty or stenting could lower deaths.
Combining a minimally invasive surgery with clot-busting drugs may be a safe way to remove clots from deep inside the brain, according to new research. Intracerebral hematoma ? a blood clot caused by bleeding from a ruptured vessel in the brain ? is associated with high death rates and severe disability.
For elderly women, the location of excess fat may be more important for their cardiovascular health than overall obesity, according to a surprising new study published in today’s rapid access issue of Circulation: Journal of the American Heart Association. In a study of 1,356 women ages 60-85, Danish researchers found that those with excessive peripheral fat ? located in the arms, legs, hips and buttocks ? had less atherosclerosis than those whose fat was stored mostly in their abdominal area (visceral fat) and other central parts of the body.
People with short upper legs are more likely to have glucose intolerance or diabetes, researchers reported today at the American Heart Association’s 43rd Annual Conference on Cardiovascular Disease Epidemiology and Prevention. The study seems to support the hypothesis that factors influencing growth in the womb and during childhood may contribute to the development of impaired glucose tolerance and diabetes, says Keiko Asao, M.D., M.P.H., and a Ph.D. candidate at Johns Hopkins University in Baltimore, Md. Impaired glucose tolerance is also called insulin resistance. It’s a metabolic disorder in which the body cannot efficiently turn blood sugar (glucose) into energy.
Women should make lifestyle changes and lower their cholesterol before menopause, when their risk for heart disease begins to increase, according to a study reported today at the American Heart Association’s 43rd Annual Conference on Cardiovascular Disease Epidemiology and Prevention.