High-power ultrasound, currently used for cell disruption, particle size reduction, welding and vaporization, has been shown to be 99.99 percent effective in killing bacterial spores after only 30 seconds of non-contact exposure in experiments. In the experiments, bacterial spores contained in a paper envelope, were placed slightly (3mm) above the active area of a specially equipped source of inaudible, high frequency (70 to 200 kHz) sound waves and hit for 30 seconds. There was no contact medium, such as water or gel, between the ultrasound source and the spores as is typically used in low-power, medical diagnostic ultrasound. The experiments mark the first time that Non-Contact Ultrasound (NCU) has been shown to inactivate bacterial spores.