Indiana University scientists have solved a perplexing mystery regarding one of the body’s main energy storage molecules, in the process shedding light on a possible route to treatment of a rare but deadly disease in teenagers.
The disease occur…
INDIANAPOLIS — An antibiotic known for its immunosuppressive functions could also point the way to the development of new anti-cancer agents, researchers at the Indiana University School of Medicine have reported.
The study determined that the c…
Researchers have proved that a single “master switch” enzyme, known as aldose reductase, is key in producing excess mucous that clogs the airways of people with asthma and chronic obstructive pulmonary disease (COPD). The enzyme’s action can be bloc…
MicroRNAs (miRNAs) regulate gene expression by mainly binding to the 3′-UTR of target mRNAs, leading to mRNA degradation or translation inhibition. Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies in China. Many…
Richmond, Va. (Dec. 3, 2010) — Research at Virginia Commonwealth University Massey Cancer Center led by Charles E. Chalfant, Ph.D., associate professor of biochemistry and molecular Biology, discovered a previously unknown mechanism in non-sma…
Athens, Ga. ¬¬– New University of Georgia research, published this week in the early online edition of the journal Proceedings of the National Academy of Sciences, has found that blocking the action of an enzyme called GnT-V significantly delays t…
Scientists have identified a mysterious culprit that threatens headaches, stuffy noses, skin rash and other allergy symptoms when more than 500 million people worldwide drink wine. The discovery could help winemakers in developing the first low alle…
ST. LOUIS — Using state-of-the-art robotic and x-ray crystallographic equipment, researchers at Saint Louis University have revealed for the first time the molecular structure of the zymogen, or inactive, form of a blood-clotting enzyme.
In an …
Scientists have discovered the secret of how an amazing sea snail injects its venom after shooting a harpoon-like tooth into its prey — or some unlucky swimmer — at jetliner speeds. The creatures, called cone snails, use a highly specialized s…
Information on proteins is critical for understanding how cells function in health and disease. But while regular proteins are easy to extract and study, it is far more difficult to gather information about membrane proteins, which are responsible f…
EAST LANSING, Mich. — The discovery of a hormone acting like molecular glue could hold a key to bolstering plant immune systems and understanding how plants cope with environmental stress.
The study, which is featured in the Oct. 6 issue of Nat…
ST. LOUIS — Thanks to a discovery by a Saint Louis University researcher, scientists have identified an important microRNA that may allow us to better control cholesterol levels in blood.
Led by Ángel Baldán, Ph.D., assistant professor of bio…