Birth is a time of peril for the human brain, especially in pre-term infants. For vulnerable “preemies,” biochemical signs of reduced blood oxygen levels (hypoxia) soon after birth are associated with lower IQs and language skills. In 2001, premature babies were 12 percent of U.S. births – the highest level in 20 years, due in part to more multiple pregnancies, induced labor, and older mothers. The January issue of Neuropsychology, published by the American Psychological Association (APA) reports on links among pre-term birth, risk for birth hypoxia and cognitive problems, and reveals how the risk threshold for brain damage in preterm babies could be lower than thought.