Overweight and obese individuals incur up to $1,500 more in annual medical costs than healthy-weight individuals, according to a two-year study of nearly 200,000 employees of General Motors. Average annual medical costs for normal weight individuals in the study were $2,225, while costs for overweight and obese individuals rose steadily, from $2,388 for overweight individuals to $3,753 for the most severely obese persons. The study, by Dee W. Edington, Ph.D., of the University of Michigan and colleagues, is the first to examine the relationship between medical costs and the six weight groups defined by the National Heart, Lung and Blood Institute’s weight guidelines. The guidelines separate individuals into categories of underweight, healthy-weight, overweight and three different obesity designations, based on average body mass index.