An international team of researchers has made new links between 29 regions of the genome and ulcerative colitis — a common form of inflammatory bowel disease (IBD). The new findings increase the total number of genome regions known to be associate…
Scientists at the University of California, San Diego School of Medicine have described for the first time a key inhibitory role for the IL-1 signaling pathway in the human innate immune system, providing novel insights into human inflammatory bowel…
Scientists at the Virginia Bioinformatics Institute at Virginia Tech have discovered some of the key molecular events in the immune system that contribute to inflammatory bowel disease. The results, which help researchers move one step further in th…
An international team of researchers led by the University of East Anglia (UEA) have developed a new kind of endoscope to aid the early detection and diagnosis of inflammatory bowel disease.
The Confocal Laser Endomicroscope (CLE) contains a powe…
By the end of this year, colonoscopy screening will have prevented bowel cancer in approximately 99 000 people since it was introduced in Germany. This is the result obtained by Hermann Brenner of the German Cancer Research Center in Heidelberg and …
Laparoscopic or ‘keyhole’ surgery is a safe, effective way of removing bowel tumours and should be offered to all patients undergoing surgery for colorectal cancer, according to researchers from the University of Leeds.
Patients who have laparosco…
Researchers at the Georgia Institute of Technology and Emory University have developed a novel approach for delivering small bits of genetic material into the body to improve the treatment of inflammatory bowel diseases. Delivering short strands o…
EAST LANSING, Mich. — Fish oil — long encouraged by doctors as a supplement to support heart and joint health, among other benefits — induced severe colitis and colon cancer in mice in research led by Michigan State University and published t…
Certain bacteria that inhabit the intestine provide the environmental trigger that initiates and perpetuates chronic intestinal inflammation in individuals who are genetically susceptible to inflammatory bowel disease (IBD), a study led by Harvard S…
A significant breakthrough by scientists at Cardiff University and the University of Edinburgh will enable new drugs to be developed, which could prevent bowel cancer. Researchers led by Professor Adrian Bird at Edinburgh and Professor Alan Clarke at Cardiff have discovered a gene, called MBD2, which is essential for bowel cancer cells to grow, but is dispensable in normal cells. The findings of the research, funded in part by the Wellcome Trust and published in the journal Nature Genetics, raise the possibility that drugs which inactivate MBD2 could prevent human bowel cancer without harming normal cells.