Scientists may have discovered why the brain’s higher information-processing center slows down in old age, affecting everything from language, to vision, to motor skills. The findings may also point toward drugs for reversing the process.
A brain chemical called GABA helps neurons stay finicky about which signals they respond to – a must for the brain to function at its peak. Certain neurons in very old macaque monkeys lose their pickiness, researchers have found, seemingly because they don’t get enough GABA. These results appear in the journal Science, published by the American Association for the Advancement of Science (AAAS).