cell leukemia Archives

Zebrafish may point the way toward genes responsible for T cell leukemia

Scientists hunting for genes responsible for acute lymphoblastic leukemia have a new compass: a system that uses powerful genetic techniques in a zebrafish model. Researchers report they have created a zebrafish model that will help scientists pinpoint genes that accelerate or delay the spread of T cell acute lymphoblastic leukemia (ALL), a disease responsible for 400 deaths – about half of them, children – in the United States each year. The model may also provide a faster, more direct way of testing novel drugs against the disease.

Researchers develop first-ever animal model for a common form of lymphoma

Researchers have developed the world’s first animal model for mature human B-cell lymphomas, a discovery that may lead to the uncovering of the genetic mutations that cause these types of cancer. Mature B-cell type lymphomas account for about 85 percent of all lymphomas, and include both Hodgkin’s and non-Hodgkin’s lymphomas.