COLUMBIA, Mo. — Nobody enjoys colonoscopies, including mice. University of Missouri researchers are excited about the potential of using genetic biomarkers to predict colon cancer caused by inflammation. A new method developed at the MU Re…
An international team of researchers has made new links between 29 regions of the genome and ulcerative colitis — a common form of inflammatory bowel disease (IBD). The new findings increase the total number of genome regions known to be associate…
Scientists at the University of California, San Diego School of Medicine have described for the first time a key inhibitory role for the IL-1 signaling pathway in the human innate immune system, providing novel insights into human inflammatory bowel…
An international team of researchers led by the University of East Anglia (UEA) have developed a new kind of endoscope to aid the early detection and diagnosis of inflammatory bowel disease.
The Confocal Laser Endomicroscope (CLE) contains a powe…
PHILADELPHIA – A recently identified immune cell that directs other cells to fight infection plays a critical role in regulating the immune system in both health and disease. Researchers from the University of Pennsylvania School of Medicine h…
Certain bacteria that inhabit the intestine provide the environmental trigger that initiates and perpetuates chronic intestinal inflammation in individuals who are genetically susceptible to inflammatory bowel disease (IBD), a study led by Harvard S…
A preliminary study reports that enhancing the body’s innate immunity can improve symptoms of Crohn’s disease in 80 percent of patients with moderate to severe forms of the debilitating, inflammatory gastrointestinal disorder. Crohn’s disease is a chronic, lifelong condition, which affects about half a million people in the United States. Until now, the disease has been thought to result from an overactive immune system, and therapies have attempted to suppress, rather than enhance, the immune response. Therapies that suppress immunity improve symptoms in many Crohn’s disease patients, but researchers are looking for alternative treatments to help those who don’t respond.