ANN ARBOR, Mich.—DNA, that marvelous, twisty molecule of life, has an alter ego, research at the University of Michigan and the University of California, Irvine reveals.
On rare occasions, its building blocks “rock and roll,” deforming the famil…
The twisting, ladder-like form of the DNA molecule — the architectural floor plan of life — contains a universe of information critical to human health. Enormous effort has been invested in deciphering the genetic code, including, most famous…
CHAMPAIGN, Ill. — Thanks to a single-molecule imaging technique developed by a University of Illinois professor, researchers have revealed the mechanisms of an important DNA-regulating enzyme.
Helicase enzymes are best known for “unzipping…
Yards of DNA are packed into cells by wrapping the DNA around proteins called nucleosomes. But that tight packing makes it hard for the cell’s machinery to get at the DNA code to read, copy or repair it. Now researchers at the University of California, Davis, have shown how two proteins form a molecular machine that shuffles the nucleosomes out of the way to expose the DNA double helix.