Troy, N.Y. — A few unassuming drops of liquid locked in a very precise game of “follow the leader” could one day be found in mobile phone cameras, medical imaging equipment, implantable drug delivery devices, and even implantable eye lenses.
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Using a lab technique called domain insertion, researchers have joined two proteins in a way that creates a molecular “switch.” The result, the researchers say, is a microscopic protein partnership in which one member controls the activity of the other. Similarly coupled proteins may someday be used to produce specialized molecules that deliver lethal drugs only to cancerous cells. They also might be used to set off a warning signal when biological warfare agents are present.