A team of researchers at the University of Gothenburg, Sweden, has identified an enzyme that protects against inflammation and joint destruction. Made when the researchers blocked production of the enzyme GGTase-I in transgenic mice, this unexpected…
If you think histamines are your nemesis during allergy season, here’s something that might change your perspective. New research published in the Journal of Leukocyte Biology (http://www.jleukbio.org) shows that histamine could be an important mole…
LEXINGTON, Ky. (Jan. 4, 2011) − Scientists at the University of Kentucky have discovered that plasminogen, a protein used by the body to break up blood clots, speeds up the progress of prion diseases such as mad cow disease.
This finding m…
An unexpected discovery by UCLA life scientists holds promise for the future development of treatments for post-traumatic stress disorder and other anxiety disorders, and potentially for Alzheimer’s disease and other memory-impairment diseases.
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For decades, doctors have looked at fitness levels, weight, and overall health risk factors for heart disease and stroke. Now, they may soon add a new risk factor to the list: activation of the complement system. The complement system is usually imp…
The joy of a juicy hamburger could make a comeback thanks a new discovery by scientists from the University of Kentucky. In a new research report in the December 2010 print issue of The FASEB Journal (http://www.fasebj.org), scientists found that a …
Scientists are keeping their eye on a new discovery published in the November 2011 print issue of the FASEB Journal (http://www.fasebj.org) that explains what causes some genes to go out of control. Scientists have identified a “cellular switch,” ca…
Researchers from Mount Sinai School of Medicine have identified a mechanism controlling the function of a protein that binds to DNA during embryonic development and may function to prevent abnormal tumor growth. When the protein, TCF3, is modified b…
JACKSONVILLE, Fla. — Researchers at Mayo Clinic in Florida have found that a molecule long believed to be a beneficial tumor suppressor — and thus a potential cancer drug target — appears to act as an oncogene in some lethal brain tumors.
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For the first time, researchers have discovered a disease mechanism that links hereditary amyotrophic lateral sclerosis to the more common “sporadic” form of ALS — and points to a possible therapeutic target.
The findings are reported online in a…
Scientists at Washington University School of Medicine in St. Louis have discovered a new drug target that could improve the effectiveness of radiation for hard-to-treat cancers.
The finding, published in the Journal of the National Cancer Institu…
Tumor cells have evolved a crafty scheme for protecting themselves from the killing power of the host immune system; in part, they disable the immune response. New studies implicate a receptor for prostaglandin E2 (PGE2) in this phenomenon of tumor-induced immune suppression. The findings, published in the March 1 Journal of Clinical Investigation, suggest that drugs that block the PGE2 receptor, called EP2, might restore the immune system’s tumor-killing capacity.