T-regulatory lymphocytes (Tregs) are a subset of T lymphocytes that are involved in the mechanism of immunotolerance to self- and allo-antigens. Activity of these cells is one of the mechanisms of immune evasion of tumors, which inhibits the antitum…
Sphincter of Oddi dysfunction (SOD) is a pathological syndrome that is usually classified into the biliary type or the pancreatic type according to the Milwaukee criteria. However, this classification has some drawbacks in clinical practice, some of…
Patients undergoing liver surgery have long been considered to be at low risk of venous thromboembolism. However, pulmonary embolism has recently emerged as an increasingly frequent and potentially fatal complication following liver resections.
A …
E2F5 is a member of the E2F transcription factor family, and plays a key role in cell growth and proliferation. Overexpression of E2F5 has been reported in various human cancers, but not in liver cancer, and its biological implication is largely unk…
Iron overload is a common and serious problem in thalassemic major patients. As iron accumulation is toxic in the body’s tissues, accurate estimation of iron stores is of great importance in these patients to prevent iron overload by an appropriate …
MicroRNAs (miRNAs) regulate gene expression by mainly binding to the 3′-UTR of target mRNAs, leading to mRNA degradation or translation inhibition. Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies in China. Many…
Hemolysis is not uncommon during cardiovascular surgery, resulting in elevated circulating levels of cell-free oxyhemoglobin (FHb). The effect of hemolysis on intestinal microcirculation and gut wall integrity is unclear.
A research article to be …
Low-dose acetylsalicylic acid (ASA) has been widely used for prevention of cardiovascular and cerebrovascular events. Several studies have shown that mucosal breaks caused by taking low-dose ASA occurred not only in the upper gastrointestinal tract …
PROVIDENCE, RI — A new study from Rhode Island Hospital found that 33 individuals were responsible for 305 cases of medical intervention to remove foreign bodies that were intentionally swallowed, resulting in more than $2 million in estimated…
PROVIDENCE, RI — A new multi-center study of 854 children with Crohn’s disease shows a 5-year cumulative risk of bowel surgery is significantly lower than reported in recent studies. The findings of the study, led by Hasbro Children’s Hospital…