Using a $225,000 microscope, researchers have identified the key components of a protein called TRIM5α that destroys HIV in rhesus monkeys.
The finding could lead to new TRIM5α-based treatments that would knock out HIV in humans, said se…
Mayo Clinic researchers have identified a naturally occurring “good guy” for patients infected with HIV. It is a helpful gene mutation that impairs the HIV virus’ cell-killing machinery, thus preserving immune system function. Moreover, Mayo’s experiments in mice suggest that the presence or absence of this mutation in the gene known as Vpr may play a central role in determining which HIV-infected patients develop full-blown, fatal AIDS.
A molecule that naturally degrades a protein linked to Alzheimer’s disease appears to reduce the levels of that protein by nearly 50 percent when delivered by gene therapy, researchers at the Salk Institute and UC San Diego have found in collaboration with researchers at the University of Kentucky. The findings appear in the March 15 issue of the Journal of Neuroscience.