Quest for designer bacteria uncovers a ‘Spy’

ANN ARBOR, Mich.—Scientists have discovered a molecular assistant called Spy that helps bacteria excel at producing proteins for medical and industrial purposes.
Bacteria are widely used to manufacture proteins used in medicine and indus…

Unlocking the secret(ase) of building neural circuits

LA JOLLA, CA — Mutant presenilin is infamous for its role in the most aggressive form of Alzheimer’s disease — early-onset familial Alzheimer’s — which can strike people as early as their 30s. In their latest study, researchers at the Sal…

Penn study identifies molecular guardian of cell’s RNA

PHILADELPHIA – When most genes are transcribed, the nascent RNAs they produce are not quite ready to be translated into proteins – they have to be processed first. One of those processes is called splicing, a mechanism by which non-coding gene…

‘Reaper’ protein strikes at mitochondria to kill cells

Our cells live ever on the verge of suicide, requiring the close attention of a team of molecules to prevent the cells from pulling the trigger. This self-destructive tendency can be a very good thing, as when dangerous precancerous cells are permit…

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