Gene that makes people vulnerable to leprosy discovered

An international research team has identified a gene on human chromosome 6 that makes people vulnerable to leprosy. The study will be published in the March 2003 issue of Nature Genetics. Leprosy, a chronic disease caused by infection with the bacteria Mycobacterium leprae, affects approximately one million people worldwide. While it is a rare disease in Canada and the United States, the World Health Organization has identified 91 countries in which leprosy infection is highly prevalent. Symptoms of leprosy include pigmented skin lesions, permanent nerve damage leading to numbness of the feet and hands and, if left untreated, the disease may result in gross disfiguration including loss of finger, toes, feet and hands.