insulin
Type 2 diabetes linked to single gene mutation in 1 in 10 patients
A multinational study has identified a key gene mutation responsible for type 2 diabetes in nearly 10 percent of patients of white European ancestry.
The study, which originated in Italy and was validated at UCSF, found that defects in the HMGA1 g…
Missing sugar molecule raises diabetes risk in humans
Researchers at the University of California, San Diego School of Medicine and Rady Children’s Hospital-San Diego say an evolutionary gene mutation that occurred in human millions of years ago and our subsequent inability to produce a specific kind o…
Home urine test measures insulin production in diabetes
A simple home urine test has been developed which can measure if patients with Type 1 and Type 2 diabetes are producing their own insulin. The urine test, from Professor Andrew Hattersley’s Exeter-based team at the Peninsula Medical School, replaces…
La Jolla Institute-led team illuminates cell pathway key to insulin resistance in Type 2 diabetes
SAN DIEGO — (February 24, 2011) — A research team, led by La Jolla Institute scientist Joel Linden, Ph.D., has shed new light on the problem of insulin resistance, and identified the key participants in a molecular pathway that holds therapeu…
New clues uncover how ‘starvation hormone’ works, investigators at UT Southwestern report
DALLAS — Dec. 26, 2010 — New findings by UT Southwestern Medical Center researchers may solve a 17-year-old mystery about how the so-called “starvation hormone” affects multiple biological systems, including preventing insulin sensitivity and pr…
BUSM researchers uncover cellular mechanism responsible for chronic inflammation, Type 2 diabetes
(Boston) — Researchers from Boston University School of Medicine (BUSM) have demonstrated that certain T cells require input from monocytes in order to maintain their pro-inflammatory response in people with type 2 diabetes (T2D). The study also s…
Understanding diabetes at the molecular level
United States and Japanese researchers have identified a key step in metabolic pathways linked to diabetes and cancer. The study on activation of the protein complex TORC 2 was published online in the journal Current Biology Oct. 28.
TORC 2 activa…
Insulin-creating cell research may lead to better diabetes treatment
LIVERMORE, Calif. — Beta cells, which make insulin in the human body, do not replicate after the age of 30, indicating that clinicians may be closer to better treating diabetes.
Type 1 diabetes is caused by a loss of beta cells by auto-immunity …
