The burning, tingling pain of neuropathy may affect feet and hands before other body parts because the powerhouses of nerve cells that supply the extremities age and become dysfunctional as they complete the long journey to these areas, Johns Hopkin…
The current focus on medical errors isn’t quite as new as it seems. A Johns Hopkins review of groundbreaking neurosurgeon Harvey Cushing’s notes, made at the turn of the last century, has turned up copious documentation of his own surgical mishaps a…
An ambitious hunt by Johns Hopkins scientists for actively “jumping genes” in humans has yielded compelling new evidence that the genome, anything but static, contains numerous pesky mobile elements that may help to explain why people have such a var…
A myriad of inputs can indicate a body’s health bombard pancreatic beta cells continuously, and these cells must consider all signals and “decide” when and how much insulin to release to maintain balance in blood sugar, for example. Reporting in N…
A prescribed set of hospital-wide patient-safety programs can lead to rapid improvements in the “culture of safety” even in a large, complex, academic medical center, according to a new study by safety experts at Johns Hopkins.
“It doesn’t take de…
Scientists have solved an important mystery about why an arsenic compound, called arsenite, can kill us, and yet function as an effective therapeutic agent against disease and infections. According to new research published in the October 2010 issue…
Researchers have found that a recently discovered gene plays an essential role in mediating apoptosis, or cell death, in colorectal cancer cells. The gene, PUMA, or p53 up-regulated modulator of apoptosis, is controlled by p53 ? a tumor-suppressing gene that prevents normal cells from turning into life-threatening tumor cells. Previous research has determined that damage to p53 is fundamental to the development of a vast majority of cancers, and inactivation of the growth-controlling function of p53 is critical to the growth and spread of most cancers.
The greater use of intensivists, physicians who specialize in the management of critically ill patients, in intensive care units (ICUs) significantly reduces ICU mortality, hospital mortality and length of stay, according to a study published by University of Pittsburgh School of Medicine and Johns Hopkins University School of Medicine researchers.
Results of an animal study published in the journal Science raise the possibility that the use of the rave fave drug Ecstasy ? methylene-dioxymethamphetamine ? can damage brain cells. The same cells, in fact, that are destroyed by Parkinson?s disease.
“We don’t know if human beings develop the same effects we describe in monkeys and in baboons,” Dr. George Ricaurte, a Johns Hopkins neurologist, told Reuters. “The broader issue is, are there hundreds of cases of unexplained parkinsonism in MDMA users? We don’t know because we haven’t looked.”
The Reuters article also contains the following quotation, reproduced below only marginally out of context: “[A]s you might imagine, it is not easy to get a baboon to take an oral dose of a drug.”