Scientists bioengineer a protein to fight leukemia

LOS ANGELES (February 18, 2011) — Scientists at the Children’s Center for Cancer and Blood Diseases and The Saban Research Institute of Children’s Hospital Los Angeles today announced a breakthrough discovery in understanding how the body figh…

Super Bowl losses can increase cardiac death

A new study published in the journal Clinical Cardiology reveals that a Super Bowl loss for a home team was associated with increased death rates in both men and women and in older individuals.
Sports fans may be emotionally involved in watching th…

Bionic Eye Completes First Phase Of Testing

Researchers from the Keck School of Medicine of the University of Southern California, its Doheny Retina Institute and Second Sight, LLC, are reporting on the initial results of their groundbreaking, FDA-approved feasibility trial of an intraocular retinal prosthesis that appears to be able to restore some degree of sight to the blind.
“We have successfully completed enrollment and implantation of three patients in the trial,” says Mark Humayun, M.D., professor of ophthalmology at the Keck School. “And we have found that the devices are indeed electrically conducting, and can be used by the patients to detect light or even to distinguish between objects such as a cup or plate in forced choice tests conducted with one patient so far.”

Components of diabetes in African Americans have genetic underpinnings

American children whose genetic roots strongly reach back to Africa are less sensitive to insulin-a factor important in the development of type 2 diabetes-than those whose ancestors hailed heavily from Europe, according to study results released today. Rather than relying on broad categories of race, such as black or white, researchers in diabetes and obesity from the Keck School of Medicine of USC and the University of Alabama at Birmingham analyzed a group of children for 20 key genetic markers found far more often in those of African descent than those of European descent. They found that the more African-origin markers in children’s genetic makeup, the less their bodies responded to insulin-and the more insulin in their blood.

Oral drug turns on silenced genes, turns off cancer

Oral administration of a drug that inhibits a process known as DNA methylation results in a reduction in the size of malignant tumors in mice, according to a team of researchers led by scientists from the Keck School of Medicine of the University of Southern California. The drug, called zebularine, accomplishes its tumor-whittling by turning on tumor suppressor genes that have been turned off by methylation.