An Italian research team confirmed that the scoring system for Wilson’s disease (WD) provides good diagnostic accuracy with 93% positive and 92% negative predictive values, respectively in children with mild liver disease. In asymptomatic children, …
ANN ARBOR, Mich. — A University of Michigan-led research team has identified a gene responsible in some families for a devastating inherited kidney disorder, thanks to a new, faster method of genetic analysis not available even two years ago….
WASHINGTON — Older adults with diabetes who have high blood pressure, walk slowly or lose their balance, or believe they’re in bad health, are significantly more likely to have weaker memory and slower, more rigid cognitive processing than those …
Mice lacking only one copy of the gene for CD2-associated protein (CD2AP) appear to be significantly more susceptible to kidney disease and failure than normal mice. Moreover, the mutation appears to impair the elimination of proteins that accumulate in the kidney, a previously unidentified process.
A team led by University of Massachusetts Amherst researcher Deborah J. Good has identified a gene that appears to play a role in obesity, physical activity, and sex behaviors in mice. Good works with so-called “knock-out” mice, which have a specific gene deleted. Scientists then monitor the animals for changes in their physiology and behavior, in an effort to determine the gene’s role. Her findings are detailed in the current issue of the journal Physiology and Behavior. The project is funded with a four-year, $1 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, and a two-year, $70,000 grant from the National Institute of Child Health and Human Development, both of the National Institutes of Health.