mark mattson

Meal Skipping Helps Rodents Resist Diabetes, Brain Damage

A new mouse study suggests fasting every other day can help fend off diabetes and protect brain neurons as well as or better than either vigorous exercise or caloric restriction. The findings also suggest that reduced meal frequency can produce these beneficial effects even if the animals gorged when they did eat, according the investigators at the National Institute on Aging (NIA). ?The implication of the new findings on the beneficial effects of regular fasting in laboratory animals is that their health may actually improve if the frequency of their meals is reduced,? says Mark Mattson, Ph.D., chief of the NIA?s Laboratory of Neurosciences.

Fasting forestalls Huntington's disease in mice

Decreasing meal frequency and caloric intake protects nerve cells from genetically induced damage, delays the onset of Huntington’s disease-like symptoms in mice, and prolongs the lives of affected rodents, according to investigators at the National Institute on Aging (NIA) Intramural Research Program. This animal study* is the first to suggest that a change in diet can influence the course of Huntington’s disease.