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md anderson cancer

Protein and microRNA block cellular transition vital to metastasis

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HOUSTON – Like a bounty hunter returning escapees to custody, a cancer-fighting gene converts organ cells that change into highly mobile stem cells back to their original, stationary state, researchers report online at Nature Cell Biology.
…

Categories Blog Entry, Health

Everolimus improves progression-free survival for patients with rare pancreatic cancer

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Houston – In an international Phase III randomized study, everolimus, an inhibitor of the mammalian target of rapamycin (mTOR), has shown to dramatically improve progression-free survival for patients with advanced pancreatic neuroendocrine tumors (…

Categories Blog Entry, Health, Life & Non-humans

MicroRNA suppresses prostate cancer stem cells and metastasis

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HOUSTON — A small slice of RNA inhibits prostate cancer metastasis by suppressing a surface protein commonly found on prostate cancer stem cells. A research team led by scientists at The University of Texas MD Anderson Cancer Center reported …

Categories Blog Entry, Health

MicroRNA-TP53 circuit connected to chronic lymphocytic leukemia

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HOUSTON – The interplay between a major tumor-suppressing gene, a truncated chromosome and two sets of microRNAs provides a molecular basis for explaining the less aggressive form of chronic lymphocytic leukemia, an international team of researchers…

Categories Blog Entry, Health

Protein wields phosphate group to inhibit cancer metastasis

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HOUSTON – By sticking a chemical group to it at a specific site, a protein arrests an enzyme that may worsen and spread cancer, an international research team led by scientists at The University of Texas MD Anderson Cancer Center reports in …

Categories Blog Entry, Health

Drugs are safe, active in patients normally ineligible for clinical trial

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ORLANDO – A two-drug combination is safe and active in newly diagnosed acute myeloid leukemia and myelodysplastic syndrome patients who are usually excluded from clinical trials because they have other illnesses or poor performance status -…

Categories Blog Entry, Health

Small molecule may disarm enemy of cancer-fighting p53

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ORLANDO — A pioneering clinical trial is testing the effectiveness in leukemia of a small molecule that shuts down MDM2, a protein that can disable the well-known tumor suppressor p53.
Michael Andreeff, M.D., Ph.D., professor of Medicine and ch…

Categories Blog Entry, Health

Wellness programs provide high returns, research reveals

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Employee wellness programs have often been viewed as a nice extra, not a strategic imperative. But the data demonstrate otherwise, according to a team of researchers led by Leonard L. Berry of Texas A&M University, Ann M. Mirabito of Baylor Universi…

Categories Blog Entry, Health

Vaccine extends glioblastoma patients’ survival in phase II trial

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HOUSTON – A vaccine that turns the immune system against brain tumor cells bearing a genetic mutation that drives the most aggressive form of glioblastoma multiforme improved survival of patients in a phase II clinical trial, researchers at Duke…

Categories Blog Entry, Brain & Behavior, Health

Targeted strategies needed to find, prevent and treat breast cancer among Mexican-origin women

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HOUSTON – Specific prevention and education strategies are needed to address breast cancer in Mexican-origin women in this country, according to a study at The University of Texas MD Anderson Cancer Center, which was published online in the journal …

Categories Blog Entry, Health

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