A Canadian biomedical company said it has confirmed that a nasal vaccine protects mice against pneumonic Plague caused by lethal aerosol infection. In a series of experiments performed by the US Army Medical and Materiel Command at Fort Detrick, Maryland, in collaboration with ID Biomedical, mice nasally immunized with Plague antigen formulated with the Proteosome technology were completely protected against lethality (100%) even when the dose of Plague antigen was ten-fold lower than ever previously given nasally. In marked contrast, none of the control mice given nasal solution without vaccine antigen survived.