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Q&A on Stanford’s Stem Cell Research Announcement

The Stanford University School of Medicine announced on Dec. 10 plans to form an Institute for Cancer/Stem Cell Biology and Medicine. This multidisciplinary institute will study both stem cell biology and cancer biology, and will attempt to apply knowledge learned from stem cell biology to new treatments for cancer.

Q: Is Stanford planning on cloning human embryos?
A: No. The new institute will study adult stem cell lines generated from individuals with specific diseases such as cancer or neurodegenerative disorders. The institute will also investigate two different ways of generating new embryonic stem cell lines ? initially in mice. This may be extended to human cell lines if the techniques prove useful.

Mutation Causes Huntington’s Symptoms

Researchers have discovered a gene mutation that causes a condition apparently identical to Huntington’s Disease, helping explain why some people with the disorder do not have a separate mutation found in most cases. The finding may help reveal why some diseases, like Huntington’s, Alzheimer’s and Parkinson’s, destroy some brain cells while sparing others. “For all practical purposes this is Huntington’s Disease, yet it’s caused by a different mutation on a completely different chromosome,” said Russell L. Margolis, M.D., associate professor of Psychiatry at Hopkins and director of the Johns Hopkins Laboratory of Genetic Neurobiology. “This is a rare version of an already rare disorder, but the mutation that causes it may not only help us better understand Huntington’s Disease, but could boost our understanding of many other neurodegenerative disorders.”