Component in plastic bottles found to cause abnormal pregnancies in mice

Researchers have found disturbing new evidence suggesting that environmental exposure to a ubiquitous substance may cause chromosomally abnormal pregnancies. They have learned that low levels of a compound used in the manufacture of common plastic food and beverage containers and baby bottles interfere with cell division in the eggs of female mice. The disruption of cell division can result in an abnormal number of chromosomes in the eggs, a condition known as aneuploidy, which is the leading cause of mental retardation and birth defects in humans. Down syndrome is an example of a disorder caused by the addition of an extra chromosome.

Biodegradable plastic imitates bacteria

Finding an economical way to make a polyester commonly found in many types of bacteria into a plastic with uses ranging from packaging to biomedical devices is a long-held scientific goal. Such a polymer would be a “green” plastic, in that it would be biodegradable. Geoffrey Coates, a professor of chemistry and chemical biology at Cornell University, Ithaca, N.Y., has partially achieved this goal by discovering a highly efficient chemical route for the synthesis of the polymer, known as poly(beta-hydroxybutyrate) or PHB. The thermoplastic polyester is widely found in nature, particularly in some bacteria, where it is formed as intracellular deposits and used as a storage form of carbon and energy. And yet it shares many of the physical and mechanical properties of petroleum-based polypropylene, with the added benefit of being biodegradable.