Antibody locks up West Nile’s infection mechanism

WEST LAFAYETTE, Ind. – Researchers have learned the structure that results when an antibody binds to the West Nile virus, neutralizing the virus by locking up its infection mechanism. The information could help scientists develop a vaccine against t…

Misfolding key to prion’s ability to kill brain cells

Researchers may have discovered the mechanism behind how prions ? pieces of protein molecules? can kill nerve cells in the brain and lead to some serious degenerative diseases. The key seems to lie in how one particular protein misfolds within an organelle inside the cell, transforming itself into a new agent and then poisoning the neuron in which it was made.