Blood lead levels are associated with increased blood pressure and the risk of clinical hypertension in women aged 40 to 59 years, according to a team of researchers from the Johns Hopkins Bloomberg School of Public Health, University of Maryland School of Medicine, Tulane University, and the Centers for Disease Control and Prevention (CDC). The study found blood pressure increased by lead levels well below the exposure levels of concern for adults set by the Occupational Safety and Health Administration (OSHA) and the levels for children set by the CDC. Blood lead levels can increase in women over the menopause, as lead is released from bone. The study is the first to document adverse health impacts as a consequence of bone lead release. It is published in the March 26, 2003, edition of the Journal of the American Medical Association (JAMA).