In patients with metastatic breast cancer, immune cells from a genetically matched donor can attack and shrink tumors, researchers from the National Cancer Institute (NCI) announced today at the Annual Meeting of the American Society of Clinical Oncology in Chicago. This is the first time researchers have clearly demonstrated this type of immune response, known as a graft-versus-tumor effect, acting against breast cancer.
Scientists are using new imaging technology to help them perform “virtual biopsies,” ? biological profiles of specific tumors that may help predict a patient’s response to treatment and probability of long-term survival. This whole new realm of imaging is called functional MRI (magnetic resonance imaging), a process that offers insight into a tumor’s character, not just its superficial structure.
A controversial vaccine against HIV, the virus that causes AIDS, has been shown to stimulate a critical part of the HIV-specific immune response in chronically infected patients. The small study conducted by researchers at Massachusetts General Hospital (MGH) finds that a vaccine made from an inactivated form of the AIDS virus (Remune) induces the proliferation of CD4 cells ? also called T helper cells ? that specifically target HIV. Appearing in the June issue of the journal AIDS, the study is the first clear demonstration of the potential reconstitution of the immune response in chronic HIV infection. However, this pilot study was not designed to tell whether or not the vaccine would have any effect on the eventual course of the disease.
Citizens of Chicago and Seattle shouldn’t become alarmed if they see “space suit”-attired groups of people rushing around May 12. Such an event, Homeland Defense Secretary Tom Ridge noted here today, will just be part of a test of U.S. and Canadian federal, state and local government capabilities to meet a real-life terrorist radiological or biological weapons attack.
WHO has today stepped up several activities aimed at strengthening the international response to the recent emergence of Severe Acute Respiratory Syndrome (SARS). SARS is an infectious disease of unknown etiology characterized by atypical pneumonia. The disease is spread from person to person but only through close contact with a case. To date, almost all reported cases have occurred in health workers involved in the direct care of reported cases or in close contacts, such as family members. There is no evidence to date that the disease spreads though casual contact.
We all know people who can take pain or stress much better than we can, and others who cry out at the merest pinprick. We’ve heard stories of people who did heroic deeds despite horrible injuries, and stereotypes about women’s supposedly sensitivity to pain that don’t mesh with their ability to withstand childbirth’s pain. But what accounts for all these differences in how individuals feel and respond to pain? And why are some people, especially women, more frequently prone to disorders – like temporomandibular joint pain and fibromyalgia – that cause them to feel crippling pain day and night?
For the first time ever, researchers have discovered that an animal species has changed its genetic make-up to cope with global warming. In the past, organisms have shown the flexibility–or plasticity–to adapt to their surroundings, but this is the first time it has been proven a species has responded genetically to cope with environmental forces.