Most people feel full about 10 minutes after they begin eating, but for those who are obese, it may take almost twice as long for their brains to get the message, according to researchers at the University of Florida’s Evelyn F. and William L. McKnight Brain Institute. Through innovative use of neuroimaging, UF scientists successfully pinpointed when the brain responds to changing hormone levels in the body that signal satiety. The finding raises the possibility that a delayed feeling of fullness or the inability to feel satisfied while eating could perpetuate obesity, making treatment difficult, they report in the February issue of Psychiatry Annals.