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Patients Prefer ''Virtual'' Colonoscopy but Dislike Preparation

Surveying patients who were screened for colorectal cancer, investigators at the Siteman Cancer Center at Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis found that most prefer “virtual” colonoscopy to traditional screening, but most had positive appraisals of both. Patients didn’t, however, like the bowel preparation prior to either screening test.

Researchers Identify Protein that Kills Cancer Cells

Researchers at Washington University School of Medicine in St. Louis have found that a protein called cytidine uridine guanosine binding protein-2 (CUGBP2) can destroy several different types of cancer cells. When the team inserted the protein into cultured tumor cells, more than 70 percent self-destructed. The researchers found that CUGBP2 helps regulate production of cyclooxygenase-2, (COX-2), which is better known as a key culprit in arthritis.

New Tongue Reconstruction Methods Help Patients with Mouth Cancer

Surgeons have developed new techniques for reconstructing the tongue during surgery for mouth cancer. The researchers found that the new methods often restore a patient’s ability to articulate speech and swallow normal food. The findings are published in the December issue of the Archives of Otolaryngology. “As surgeons, we are most concerned about removing all of the cancer, but we also want to preserve the person’s quality of life,” says lead author Bruce H. Haughey, M.D., associate professor of otolaryngology. “This work strives to improve both.”

New Technique Lets Doctors Examine Milk Ducts for Breast Problems

A new technique enables doctors to directly examine the lining of milk ducts in the breast for early signs of cancer and other abnormalities, according to research at Washington University School of Medicine in St. Louis. The researchers used the technique, known as ductoscopy, to detect breast abnormalities in women with a condition called pathologic nipple discharge (PND).