A collaborative team of scientists led by researchers at The Medical College of Wisconsin, in Milwaukee, has used the tools of structural biology to understand how a synthetic chemical mimics abscisic acid (ABA), a key stress hormone that helps plan…
Researchers have determined the structure of a protein with a surprising feature in it: a knot. This is the first time a knot has been found in a protein from the most ancient type of single-celled organism, an archaebacterium, and one of only a few times a knot has been seen in any protein structure. This very unusual protein shape finding is a result from the NIGMS Protein Structure Initiative, a 10-year effort to determine 10,000 unique protein structures using fast, highly automated methods.