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Deceptive Strategy Shields HIV from Destruction

Researchers have discovered one way in which the human immunodeficiency virus (HIV) wins its cat-and-mouse game with the body’s immune system. The study, published in the March 20, 2003, issue of the journal Nature, shows that HIV-1, a common strain of the virus that causes AIDS, uses a strategy not seen before in other viruses to escape attack by antibodies, one of the immune system’s prime weapons against invading viruses and bacteria.

Researchers crack nature's method for creating crystals on a sphere

In a discovery that is likely to impact fields as diverse as medicine and nanomanufacture, researchers have determined how nature arranges charged particles in a thin layer around a sphere. The leap forward in understanding this theoretical problem may help reveal structural chinks in the outer armor of viruses and bacteria (revealing potential drug targets) and guide engineers designing new molecules. On a flat surface, particles that repel each other will arrange themselves to create a stable energy state, eventually settling at vertices within a lattice of identical triangles much like billiard balls at the start of a game.