A team of researchers, led by University of Kentucky ophthalmologist Dr. Jayakrishna Ambati, has discovered a molecular mechanism implicated in geographic atrophy, the major cause of untreatable blindness in the industrialized world.
Their ar…
Researchers are using a herpes virus that produces a firefly enzyme to illuminate the virus’s course of infection in mice and to help monitor the infection’s response to therapy. “This study demonstrates the feasibility of monitoring microbial infections in living animals in real time,” says study leader David A. Leib. “The technique enables us to follow an infection over time as it progresses and resolves, and we can do this repeatedly using the same animal.”